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Consequently, affected individuals continue to experience hunger and reduced metabolic rate, making weight loss particularly challenging

By shifting dietary choices away from energy-dense, highly palatable foods toward more nutritious alternatives, GLP-1 RAs offer unique insight into the neural and behavioral mechanisms underlying compulsive consumption

Preclinical studies in rodents consistently show reduced alcohol intake with GLP-1 medications, but human clinical trials have produced mixed results

Rosenstock J, Wysham C, Frias JP, Kaneko S, Lee CJ, Fernandez Lando L, et al

M., Saluja, J., Sannidhi, D., Stanford, F

Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U, Perfetti R