glp-1 drugs for sleep apnea Might Help Quell GLP-1 Weight Loss Linked To

Am J Physiol Endocrinol Metabol

Clin Diabetol

Although GLP-1s have seen incredible successes, there are still issues with tolerability issues and access not to mention opportunities for more convenient formulations

In adults with overweight or obesity (without diabetes) the semaglutide 2.4 mg dose produced an average weight reduction of about 15% of baseline body weight over ~68 weeks in the STEP 1 trial, a result that surprised many clinicians because it brought pharmacologic outcomes into a range previously associated with surgical interventions

In terms of lowering HbA1c, dulaglutide, when administered once a week, was demonstrated to be more effective than exenatide twice a day, by 1.51% vs.0.99% [94]

These are signals, not conclusions but theyre coming directly from patients, unprompted, and thats worth paying attention to, says the first author, Neil Sehgal, a doctoral student at the University of Pennsylvania in Philadelphia