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Tirzepatide, a novel twincretin drug, significantly improves weight loss and glycemic control in obese and type 2 diabetes patients, outperforming traditional treatments in clinical trials.

GLP-1s are linked to a higher risk for osteoporosis, gout, and osteomalacia in people with type 2 diabetes and obesity, new research suggests, though an additional study also points to better orthopedic outcomes in semaglutide users.

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