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For patients with a multi-year treatment horizon who want to avoid future disruption, Roman's hybrid model is a form of insurance

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[DOI] [PubMed] [Google Scholar] 8.Incretin-based drugs and intestinal obstruction: a pharmacovigilance study

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It causes a delay in gastric emptying

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This was further reinforced in their latest release in 2024 [61,62]

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Taste Changes : Altered taste can reduce appetite and enjoyment of food

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