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The antibody-antigen interaction activates complement proteins and recruits additional immune cells, producing a reaction that is qualitatively different from the simple histamine-mediated response seen with initial injections

It is potentially dangerous, which is why understanding your vial concentration is not optional

Additionally, individual physiological differences can result in variable responses to the medication

While injection site reactions are generally self-limiting and not indicative of serious complications, patients should be educated about normal versus concerning symptoms

If you take blood thinners, supplements like fish oil or vitamin E, or high-dose aspirin, you may bruise more easily