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Common adverse effects include nausea, vomiting, diarrhea, and constipation, which are generally dose-dependent and often improve with continued use

Cardiovasc Drugs Ther (2019) 33(6):6617

In our study, daily food intake was similar among cold-stressed mice, independent of genotype, suggesting that this magnitude of change from the TN to cold-stressed GLPDRKO mice was driven by factors beyond the volume of food introduced to the system

Tolerance develops as the sympathomimetic effect plateaus, requiring higher doses for the same appetite-suppressing impacta pattern that increases cardiovascular and neuropsychiatric risks

[DOI] [PMC free article] [PubMed] [Google Scholar] 242.Heller, R

Its best to talk this through with your provider.