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Incapsula incident ID: 461000720060350835-258739683323613714

Market Restraints Gastrointestinal Adverse Effects and Stringent Regulatory Requirements Restrain Market Expansion GLP-1 receptor agonists are associated with gastrointestinal side effects such as nausea, vomiting, diarrhea, and reduced appetite, particularly during treatment initiation and dose escalation

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Successful clinical trials and approval for these GLP-1 drugs led to an increase in GLP-1RAs, but once-daily use was still a barrier for some patients with diabetes or obesity because of the frequent use of needles for daily injections

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