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Storage: Store refrigerated prior to initial use

As this study showed comparable exposures between the 1G and 2G formulations of oral semaglutide that met stringent regulatory bioequivalence criteria, it is considered unlikely that there will be any clinically meaningful differences in efficacy or safety between these formulations

Dulaglutide, liraglutide and subcutaneous semaglutide have been approved for reducing the risk of major adverse cardiovascular events in adults with type 2 diabetes mellitus with established cardiovascular disease, dulaglutide is approved for use in type 2 diabetes mellitus with multiple risk factors, and both liraglutide and semaglutide have been approved for chronic weight management

Cagrilintide alone achieved 11.5%

However, both carry similar considerations regarding slowed digestion when paired with methotrexate

250-300 minutes weekly as permanent lifestyle, not temporary effort Calorie intake below normal maintenance
