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This complementary action enables greater HbA1c reductions than either agent alone, with clinical trials demonstrating additive effects on glycemic control

Moving forward, a prospective study that enrolls new initiators and follows them with standardized breath-testing would provide higher-quality data to confirm these findings

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While CGRP is most known clinically as a target for migraine treatment (anti-CGRP antibodies are major migraine drugs), its role in bone metabolism is increasingly recognized