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it may lower the absolute rates (to the same extent in the two groups) but is unlikely to bias the rates on the relative scale

J Clin Aesthetic Dermatol

Furthermore, imaging studies have shown an increased hypothalamic response to food stimuli and diminished coupling between the ventral striatum and limbic structures [26,27]

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skin-specific effects were not highlighted as a primary safety signal, though injection site reactions were noted as expected with subcutaneous administration