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The cost of treating obesity-related diseases has reached epic proportions and is estimated to cost $147 billion in the US alone (Finkelstein et al., 2009)

92 Luseogliflozin is a selective SGLT-2 inhibitor that received marketing approval on March 24, 2014, for the treatment of T2DM

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The negotiated price will be the lesser of the current net price or a percentage of the nonfederal average manufacturer price, but the extent to which this will impact AOM prices remains unclear

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PIONEER 4 PIONEER 4 was an important trial comparing the addition of oral semaglutide or liraglutide to background metformin with or without an SGLT-2 inhibitor in patients with T2DM