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Furthermore, potential crosstalk with other metabolic hormones could be a significant factor

These included being limited to those contained in TriNetX, lack of information surrounding indications for off-label use, and missing data on BMI for approximately 3% of the cohort

L., Lewis, H

Any estimated increase in relative risk must be interpreted in the context of the low overall incidence of NAION

The UK's NHS has begun evaluating GLP-1 obesity coverage, with NICE's appraisal of semaglutide for obesity resulting in conditional approval for use through specialist weight management services a restrictive but meaningful coverage expansion that will grow over time as service capacity expands

But context matters enormously here