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This article reviews current evidence on GLP-1 therapies and CKD progression, including biomarker data, clinical trial findings, and the potential role of these agents within evolving kidney disease treatment strategies

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demonstrated that GLP-1 RAs could alleviate cytoplasmic Ca 2+ overload in VSMCs in SHRs, improve the arterioles systolic and diastolic functions, and reduce BPV by upregulating Na + /Ca 2+ exchanger 1 (NCX1) expression via the Akt signaling pathway [80]

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