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This leads to a degradation of matrix proteins and an activation of MMP, thereby indicating that the interaction of DPP4 and ADA might be involved in tissue remodeling (26)

Lipid mediators are critical in resolving inflammation: a review of the emerging roles of eicosanoids in diabetes mellitus

(1) Prevention from DPP-4 degradation

Look M, et al
[DOI] [PMC free article] [PubMed] [Google Scholar] 22

Furthermore, their data proved for the first time that a mixture of GLP-1 and GIP at physiological concentrations influenced the capacity to respond to later secretory stimuli independently of insulin content [94]
