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Alongside these incretin receptor agonists, GIP receptor antagonists have garnered significant interest, driven by evidence suggesting that endogenous GIP exacerbates obesity and insulin resistance in high-fat dietary conditions [19]

Varady KA, Runchey MC, Reutrakul S, Vidmar AP, Chow LS

after the FDA lifted a full clinical hold it had placed on the Investigational New Drug Application for PGN-EDODM1

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The decision to prescribe both medications together should be made on an individual basis, taking into account the patient's complete medical history, current health status, and the specific indications for each treatment