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The first cohort included female patients who received a semaglutide or tirzepatide prescription during the study period

The Friday evening approach also aligns well with the pharmacokinetics of most GLP-1 medications

Dietary adjustments can help firm stools and reduce bowel frequency: Eat small, light meals that are low in fat and spice Include bland foods such as rice, pasta, toast, and bananas Increase soluble fibre intake (oats, psyllium husk, cooked carrots) which absorbs water Avoid insoluble fibre (raw vegetables, wholegrain cereals) temporarily Limit fatty, fried, or spicy foods that can irritate the gut Reduce artificial sweeteners (sorbitol, mannitol) which have laxative effects Consider a temporary lactose-free diet if dairy worsens symptoms It's important to continue eating, even if you have diarrhoea, to maintain nutrition

Kuwata H, Tsujii S, Fujita N, Okamura S, Iburi T, Mashitani T, et al

Specifically, Frias et al