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Eli Lilly has not announced a specific regulatory submission timeline, but Phase 3 completion and FDA filing would logically follow several years behind CagriSemas timeline
Since semaglutide works by slowing down the emptying of the stomach, some researchers and patients have questioned whether this effect could make acid reflux symptoms worse

This study, published in the New England Journal of Medicine (2016), showed that semaglutide reduced the risk of major adverse cardiovascular events compared to placebo, suggesting potential cardiovascular benefits rather than harm

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