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Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic -cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo

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[67] studied a cohort of over 400,000 T2DM patients above the age of 65 and found that DPP-4i were associated with a 21% decrease in the risk of MACEs (including myocardial infarction and ischemic stroke) with a 46% overall decrease in risk of all-cause mortality

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they found no significant difference between GLP-1 RA combination therapy vs