glp-1 drugs and dementia Microdosing, Brain Health & Alzheimer's Prevention Can blockbuster GLP-1 weight loss

Two foreign drugmakers built the entire global GLP-1 market between them

Moreover, Elkind-Hirsch et al

In one analysis, individuals with obesity treated with GLP-1s incurred significantly higher annual healthcare costs than individuals with obesity without GLP-1 use ($7000 higher in the first year, and $4200 higher in the second year) [6,78]

Gutniak M, Orskov C, Holst JJ, Ahrn B, Efendic S

PU and BP obtained funding and supervised the study

CNS GIPR KO mice resist development of diet-induced obesity To generate CNS-specific GIPR KO mice, Gipr fl/fl mice 17 were crossed to synapsin-Cre mice (Jackson Laboratories) to obtain Gipr fl/fl control mice and Gipr Syn/ mice (breeding schematic in Fig