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Clinical trial results concerning pancreas-related adverse effects have also been added The postmarketing experience section now includes reports of alopecia (hair loss) and dysesthesia (altered sense of touch)

In contrast to the case reports on altered renal function seen with exenatide, a pooled analysis of 5,594 participants from 19 randomized, controlled clinical trials of exenatide twice-daily (5 g and 10 g) showed that renal impairment-related adverse events, including acute renal failure, were rare (1.6 per 100 person-years for both groups)

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Understanding Retatrutide Retatrutide is a "triple G" agonist, acting on GLP-1, GIP, and GCG receptors

These are also known as GLP-1 agonists, incretin mimetics, or GLP-1 analogs

Side Effects and Safety Considerations The most common side effects in trials were gastrointestinal including nausea, vomiting, and diarrhoea and were dose-dependent