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Subgroup analysis for treatment durations6 months indicated a higher WL in the GLP-1RAs group (SMD=0.79, 95% CI 0.25 to 1.34)

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Although there were no differences in magnitude between conditions (P>0.11), the postprandial GLP-1 peak response to breakfast intake was delayed by 90min following sleep loss in comparison with regular sleep (P<0.02)

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54%of userslost 20% or morebody weight

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