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Obesity 28 , 11951199 (2020)

Pancreatitis: There have been rare reports of pancreatitis (inflammation of the pancreas) associated with the use of GLP-1 medications, so close monitoring by a healthcare provider is essential

[DOI] [PMC free article] [PubMed] [Google Scholar] [30].VanderVeen BN, Cardaci TD, Unger CA, NeSmith MM, Freeman JC, Bastian AV, et al

Calibration strategies often aim to interrupt this cycle, but the strength and reliability of that effect depend on dose levels that have been validated in clinical trials

Tahrani AA, Morton J

In preclinical models, GLP-1 receptor agonists appear to modulate inflammatory signalling pathways such as nuclear factor kappa B (NF-B), a key transcription factor regulating inflammatory gene expression