surmount-1 tirzepatide trial obesity without diabetes SURMOUNT 1 // Three-Year Obesty & Prevention Outcomes Tirzepatide for Obesity: Highlights from

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The FDA approved tirzepatide for managing type 2 diabetes under the brand name Mounjaro

STEP 1 Semaglutide The landmark semaglutide trial, published in the New England Journal of Medicine in 2021, randomized 1,961 adults with obesity to semaglutide 2.4 mg weekly or placebo for 68 weeks

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A stratified Cox proportional hazards model, with treatment as a fixed effect and trial-level cardiovascular risk as the stratification factor, was used for the estimation of hazard ratios (HRs) and confidence intervals (CIs) comparing tirzepatide to control