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[DOI] [PubMed] [Google Scholar] 528.Meier J.J., Gallwitz B., Askenas M., Vollmer K., Deacon C.F., Holst J.J., et al

While some studies found no difference between individuals with T2DM and matched non-diabetic controls (6769), others found plasma DPP-4 activity to be reduced in the patients, and suggested this might reflect a compensatory response to the reduced insulin sensitivity and hyperglycaemia, in an attempt to increase intact incretin hormone concentrations and improve insulin secretion (70, 71)

We still have many unanswered questions about ideal dosing, duration, and who benefits most, such as whether APOE4 gene carriers may respond differently

The initial euphoria is coming down, said Neeraj Tulara, a Mumbai-based diabetologist and general medicine expert

In fact, weight loss and improved glucose control support kidney health long-term
