glp-1 drugs and fatty liver Therapeutic Effects of Glucagon-like Peptide-1 Receptor Agonists in Non-Alcoholic Disease: A Systematic Review Glucagon‐like peptide‐1 receptor agonists (GLP‐1

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rxlist.com (Byetta ) rxlist.com (Byduron ) extended release formulation Keywords Liraglutide Trade Names: Victoza & generic Pharmacology: GLP-1 analog mechanism of action is the same as exenatide Indications: an adjunct to diet and exercise to improve glycemic control in type 2 diabetes mellitus to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with type 2 diabetes mellitus and established cardiovascular disease Pharmacokinetics: once-daily injection Side Effects: Most common : nausea, diarrhea, vomiting (similar to exenatide) Black Box Warning: RISK OF THYROID C-CELL TUMORS References: Masharani U, Kroon L (2024): Pancreatic Hormones & Antidiabetic Drugs (Chapter 41)

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As such, glomerular lesions occur which include glomerular basement membrane thickening, podocyte effacement and loss, mesangial expansion, epithelialmesenchymal transition EMT and fibrosis, collagen deposition, damage to the capillary architecture and an influx of inflammatory cells including macrophages