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PHARMACOLOGY AND MODE OF ACTION In order to appreciate the mechanism associated with the DPP-4 inhibitors, we must understand the normal function of incretin hormones
Circulation 142:12051218
Other qualifying injuries include: Bowel obstruction or ileus (with imaging/medical records) NAION (sudden vision loss) Severe persistent vomiting requiring hospitalization Other serious GI complications requiring emergency intervention However, for gastroparesis claims specifically: Yes, you need formal diagnosis , and as of August 2025, objective testing is required
Why is mucosal integrity essential for long-term metabolic stability
Diabetes, Obesity & Metabolism, 20 ,
The high lipophilicity was also associated with off-target pharmacology such as inhibition of the human ether-a-go-go-related gene (hERG) ion channel (IC 50 = 5.6 M, Table S4)
