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11 Despite the promise of these medications, they are accompanied by significant risks, including gastrointestinal issues, pancreatitis, kidney failure, gallbladder disease, and thyroid cancer

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Its renoprotective role in several animal models, including those used for aging and acute kidney injury, has also been demonstrated (2224)

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Work with your healthcare provider to taper off gradually rather than stopping abruptly, or reducing to a lower dose for maintenance, which may help soften the return of appetite