semaglutide subcutaneous Novo Nordisk announced headline results from STEP UP, a phase IIIb trial investigating 7.2 mg for obesity Compounded Semaglutide for Weight Loss

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Over the maximum follow-up of ~30 years, there were 7069 events (1937 ASCVD, 2109 heart failure, 3288 CKD and 4785 deaths)

What leads to significant weight loss for one individual might result in minimal changes for another.

Phase 1 and Phase 2 clinical pharmacokinetic and weight-change studies

These ancillary benefits of SGLT-2 inhibitors and GLP-1 receptor agonists further support their use in people with type 2 diabetes, especially in those at risk of hyperkalemia

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