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doi: 10.1016/j.mric.2014.05.001

Dehydration and kidney injury : Severe gastrointestinal side effects may lead to dehydration and acute kidney injury

Applying an ice cube or cold pack to the injection site for 30 to 60 seconds before injecting numbs the area slightly

Patients with certain GLP1R or GIPR variants may experience faster GI adaptation, while those with FTO variants may show different appetite-suppression or metabolic profiles