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Drawing medication from a vial requires a specific sequence that prevents contamination, ensures accurate dosing, and avoids the air bubble problems that frustrate new users

In addition, the treatment response observed in our analysis may also be influenced by ethnic differences, given that five RCTs recruited exclusively Japanese participants [39,40,41, 48, 49]

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Nevertheless, the theoretical risk of hyperglycaemia from glucagon signalling remains a consideration in ongoing research