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Like Ozempic , metformin isnt FDA-approved for weight loss, but doctors sometimes prescribe it off-label, particularly for: People with a BMI of 30 or higher or People with a BMI of 27 or higher and at least one weight-related condition

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In addition, among adults who have ever taken GLP-1 drugs, cost is one of the most commonly cited reasons for stopping

The SURMOUNT-1 trial provides the most comprehensive data

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Supporting the role of glucagon in increasing BAT thermogenesis, it has been shown that glucagon administration enhances BAT temperature [63]