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doi: 10.3389/fendo.2022.824269

Despite adequate oxygenation and circulation, excitatory neurotransmitters and free radicals continue to be released, phosphorus reserves are depleted, inflammatory factors are involved, and brain injury is substantial

therefore, it is recommended to avoid GLP-1R agonists in patients with a past history or family history of medullary thyroid cancer or multiple endocrine neoplasia 2 [88,89,90]

If expectations fall short, shortages or pricing issues can ensue