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Not to get too deep into the science, but a PPAR agonist delivered selectively because of GLP1 and GIP receptors may mean that we can see the insulin sensitizing benefit of this drug class without the negative side effects that prior meds in this class have suffered from

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In the same study, patients were followed for an additional 12 weeks after the last dose of bimagrumab and experienced no weight regain

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[DOI] [PubMed] [Google Scholar] 149.Vrs I., Ondi Z., Tth V.., Gergely T.G., Sghy ., Grbe A., Kemny ., Leszek P., Helyes Z., Ferdinandy P., et al