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If your thirst has not improved after 4 weeks at the same dose, consult your healthcare provider to check for underlying electrolyte imbalances

While the medication's primary side effects are gastrointestinalincluding nausea, diarrhea, and vomitinglightheadedness can occur through indirect mechanisms such as dehydration, blood pressure changes, or hypoglycemia

Lillys orforglipron (Foundayo), FDA-approved April 2026, is oral but not tirzepatide: 11.2% loss at 72 weeks, no food or water restrictions