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Preclinical and preliminary clinical evidence of semaglutides potential beneficial effects on various substance use disorders led us to evaluate if it pertained to CUD

From this perspective, receptor-level signaling alone may be insufficient to ensure durable tissue-level outcomes
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demonstrated that weekly administration of either GLP-1 RA semaglutide or dulaglutide produces a rapid, substantial and dose-dependent reduction in EAT thickness [37], that may bring to a reduction in the pro-inflammatory stimuli

Over time, this may reduce the risk of liver fibrosis and cirrhosis

Recently, Taraschi et al
