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doi: 10.1210/jc.2003-030049 155 NauckMANiedereichholzUEttlerRHolstJJOrskovCRitzelRet al

Insurers and policymakers arent just asking, Is this a good treatment? Kim said

Chaudhuri A, Ghanim H, Vora M, et al

Despite these provocative preclinical findings suggesting a targeting phenomenon that results in enhanced efficacy and improved therapeutic index for these nuclear hormone conjugates, more studies are required to delineate the mechanism for the intracellular delivery and release of the cargo along with precise pharmacokinetic analyses

The researchers noted that some of the studys findings were imprecise, and that continuous monitoring and further research will provide more precise risk estimates