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doi: 10.1097/MED.0000000000000612 322 RangwalaSMDAquinoKZhangYMBaderLEdwardsWZhengSet al

When gut bacteria ferment dietary fiber in the colon, they produce these SCFAs, which directly activate L-cells to secrete GLP-1

Elashoff, M

37 Some studies suggest that lean mass loss with GLP-1 RAs can constitute 20-50%, sometimes even up to 60%, of total weight lost, although this proportion is often similar to or slightly better than diet-only approaches

2023 Tirzepatide (Zepbound) is approved for obesity

Liakos et al
