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The COR-I trial, involving 1,742 participants over 56 weeks, demonstrated 6.1% average weight loss with Contrave versus 1.3% with placebo (Greenway et al., Obesity, 2010)

Rapid turnaround time of 48-hours or less

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A molecule from TransTech Pharma, TTP054, is presently undergoing phase 2 clinical trials (Mullard, 2014)

GLP-1 receptor agonists and sight-threatening ophthalmic complications in patients with type 2 diabetes

Las nuevas molculas orales, en cambio, interactan con regiones distintas del receptor, lo que les permite activar de forma preferente ciertas rutas de sealizacin beneficiosas sin estimular aquellas relacionadas con efectos no deseados