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Retatrutide activates all three: GLP-1, GIP, and glucagon
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Osumili B, Fan L, Paik JS, et al
Trials so far have shown superiority of GLP-1 receptor agonists and SGLT2 inhibitors in MACE reduction when compared to DPP-4 inhibitors
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Weeks 5 through 8: 4mg weekly The first dose increase doubles the amount
