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Your GP or specialist weight management service will review your complete medical history, including: The reason for cholecystectomy and time since surgery Any ongoing post-surgical symptoms or complications Current medications and potential drug interactions Presence of other gastrointestinal conditions Liver function and metabolic health status History of pancreatitis or pancreatic disease Pregnancy status or plans (GLP-1 RAs are contraindicated in pregnancy and breastfeeding) Baseline investigations typically include blood tests to assess liver function, kidney function, HbA1c (for diabetes screening), and lipid profile

Some studies suggest yerba mate polyphenols have anti-inflammatory properties, which could indirectly support metabolic health

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For example, as a result of the weight loss and the regulation of sugar, you should also see your HbA1c (blood sugar), blood pressure and cholesterol/triglycerides improve

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Breaking that medicine into smaller doses would make it hard to measure a consistent dose and increases your risk of infection (from reusing the syringe)