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Here is a clear breakdown: This additional glucagon mechanism may contribute to the stronger weight loss outcomes observed in clinical trials

The mechanisms likely include: Chronic inflammation from excess adipose tissue Hormonal imbalances (particularly estrogen and insulin) Immune system dysfunction Cellular stress and DNA damage By addressing obesity, GLP-1 agonists may interrupt these cancer-promoting pathways

DPP4i also regulate TG excursion following meals or oral lipid challenge in mice and humans (5, 9, 10, 14)

Asano, Y

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Ideal candidates include adults who have attempted medical weight loss through diet and exercise without achieving lasting results, those experiencing metabolic resistance related to age or hormonal changes, and individuals seeking to reduce cardiovascular risk factors alongside body weight