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Avoid prolonged exposure to very cold environments if possible, and stay well-hydrated, as dehydration can amplify the sensation of being cold

Patients should understand: the importance of maintaining hydration despite reduced appetite, which symptoms warrant medical contact, how to use oral rehydration solutions if needed, and the value of keeping scheduled follow-up appointments

If nausea from tirzepatide makes this challenging, electrolyte solutions and clear broths count toward your fluid goals

[DOI] [PubMed] [Google Scholar] 70.Ying L., Butensky S., Ilang-Ying Y., Ghiassi S

Jastreboff et al., 2023 (NEJM): estudio fase 2 en adultos con obesidad sin diabetes, reduccin ponderal media de 24.2% a la semana 48 con 12 mg semanales, el mayor efecto reportado para un frmaco incretnico hasta la fecha de publicacin