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[DOI] [PubMed] [Google Scholar] 8.Neeland I.J., Linge J., Birkenfeld A.L

doi:10.1016/j.diabres.2013.12.041 31

Exceptionally, in a Phase 2a study of cotadutide, individual plasma amino acid profiles were reported

Therefore, dietary supplementation considerations for preserving and promoting muscle mass should be part of the patient-centered care plan

Specifically, the abundance of some butyrate-producing bacteria (such as the phylum Firmicutes and genus Bifidobacterium ) was reduced, while Gram-negative bacteria were relatively enriched such as the phyla Bacteroidetes and Proteobacteria (30, 31)

As a general procedure, the investigators directly performing the experimental procedures were not blinded to the group allocation, but data analyses by senior authors were largely conducted independently to avoid potential bias
