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Description
In head-to-head trials against semaglutide, the most potent available GLP-1 receptor agonist, tirzepatide demonstrated meaningfully greater improvements in both glycemic control and weight reduction

[1] [2] Patients should discuss perioperative management with their healthcare team, as these medications can affect gastric emptying and may need to be temporarily discontinued before certain procedures

GLP-1 agonists work by mimicking the action of naturally occurring GLP-1, an incretin hormone released from the intestinal L-cells in response to food intake
59 SchickR

This guide summarizes CDC and WTW data on GLP-1 usage, access challenges, and the cost implications shaping employer and patient decisions
doi: 10.1001/jamacardio.2017.2275 19 SoliniAGianniniLSeghieriMVitoloETaddeiSGhiadoniLet al
