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Another future direction of utilising GLP-1/GIP/glucagon receptor triagonists is for MASH therapy with the rationale that as GLP-1 receptor agonists halt fibrosis progression, the new therapies might be able to enable fibrosis regression [11]

This dual action produces superior weight loss outcomes in clinical trials, with nausea rates ranging from 24% to 40% depending on dose in the SURMOUNT-1 trial

Harkavyi A, Whitton PS

With ongoing research and advancements, retatrutide provides hope for individuals seeking effective management of the comorbidities associated with obesity