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In addition, risks associated with hypoglycemia are minimal and usually only occur in combination therapy with insulin secretagogues or insulin

GLP-1RAs are considered safe and reduce the risk of severe hypoglycemia in patients with chronic kidney disease

Gastrointestinal and Gallbladder Effects Gastrointestinal symptoms are usually dose-related and may be mitigated by slower titration and taking smaller, lower-fat meals during the first weeks

Currently, only one in four employers offer insurance coverage for GLP-1 drugs for weight managementwith variability in ease of access due to step therapy and prior authorization requirementswhile the majority of employers cover this class of medications for diabetes

In another case report by Fujino et al., a 31-year-old female patient on semaglutide for T2DM underwent EGD in preparation for bariatric surgery

I talked in last year's Obesity Society meeting