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Lyophilized powder should be stored at -20C

Am J Hypertens 2014

40 In one study, patients who discontinued semaglutide regained approximately 68% of their initial weight loss within one year, resulting in a net weight loss of only 5.6%

If you compare someones body composition before and after weight loss, its generally better after. Also making recent headlines is Ozempic face, or the tendency to have a saggy or sunken-in facial appearance after being on GLP-1 drugs

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doi: 10.1016/j.japh.2019.09.001 [DOI] [PubMed] [Google Scholar] 20.Kang H, Lobo JM, Kim S, Sohn M-W