glp-1 vs phentermine GLP-1s: Lower-Cost Weight Loss Options Is it safe to use

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Blood Sugar Fluctuations GLP-1 medications help regulate blood sugar, but as your body adjusts, particularly if youre eating less, you might experience occasional fluctuations in blood glucose levels

The common link is that GLP-1s activate receptors that then work on driving down metabolic risk factors through the following mechanisms: Enhancing glucose dependent insulin secretion Slowing gastric emptying and decreasing appetite Reducing postprandial glucagon and food intake UpToDate 2 : (1) ingestion of food results in (2) release of gastrointestinal peptides (GLP-1 and GIP: glucose-dependent insulinotropic polypeptide, gastric inhibitory peptide) and (3) pancreatic beta cell hormones (insulin and amylin)

Both have shown to be safe and effective in separate trials, but some research suggests that injectable versions might be marginally more effective for A1C reduction and weight loss

Coskun T, Sloop KW, Loghin C et al (2018) LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: from discovery to clinical proof of concept

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