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GLP-1 patches and oral liquid formulations represent additional delivery innovations that naturally provide more stable drug levels through continuous or frequent dosing

Press | Mechanism: GLP-1 Novos amycretin enters Phase 3 recruitment in heart failure, standing up a roughly 900-site global trial Novo Nordisks amycretin (NNC0487-0111), its next-generation GLP-1/amylin dual agonist, moved its Phase 3 HF-POLARIS trial (NCT07567001) from not-yet-recruiting to recruiting this week, activating roughly 900 clinical sites across more than two dozen countries for a 5,610-patient study in people with obesity and heart failure

21.Gill A, Hoogwerf BJ, Burger J, Bruce S, Macconell L, Yan P, Braun D, Giaconia J, Malone J

When people lose weight, they can also lose muscle mass, particularly if they are not getting enough protein or doing resistance exercises

Most studies have focused on middle-aged and older adults with Type 2 diabetes, typically those over age 50

Ingelfinger, M.D