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Participants this time were given a taste of chocolate milk while in an fMRI, but with a twist - a cue light would signal that the chocolate milk was about to be delivered through a tube, allowing the researchers to separate brain activity during anticipation (cue-triggered wanting) from activity during consumption (actual tasting pleasure)

Meta-analysis of 35 clinical trials demonstrated a modest reduction in LDL cholesterol, total cholesterol, and triglycerides in patients treated with GLP-1 RAs compared to controls (4)

Comparing semaglutide to other interventions Semaglutide produces weight loss comparable to older weight loss peptides and medications but with better tolerability and lower discontinuation rates

However, the use time and effect of GLP-1RAs, and the adverse reactions after long-term use must also be fully paid attention to and studied before clinical application
